As I see it, the advantages of this opening carry the day. It's exciting, challenging, easy to learn since the different black defences have a personality of their own and it is both educational (you'll learn a lot about structure vs material and material vs time) and practical since you only need one opening against 1 - e5.
The downside is that you really must know your stuff or you may end up on the wrong side of a miniature. But, is there any opening you can play with confidence, without knowing it?